ISSN (O): 2584-2617Frequency: MonthlyLanguages: English, Hindi and other languagesDOI Prefix: 10.62796
editor@pijst.com+91 75999 91323
PIJST logoProcedure International Journal of Science and TechnologyInternational Open Access, Peer-reviewed & Refereed JournalISSN: 2584-2617 (Online)DOI Prefix: 10.62796

Official DOI landing page

Synthesis of Some New Hydantoin Derivatives with Possible Anticonvulsant and Analgesic Activities

Dr. Roopali Tandon Corresponding Author

Department of Chemistry, Bareilly College, Bareilly, Uttar Pradesh, India

Department of Chemistry, Bareilly College, Bareilly, Uttar Pradesh, India

Department of Chemistry, Bareilly College, Bareilly, Uttar Pradesh, India

JournalPIJST
Volume / Issue1 / 6
Pages30–36
Published30 Jun 2024
Paper IDPIJST16J24005
Views / Downloads1 / 0

Article summary

Abstract

:- Literature survey on hydantoin derivatives shows various pharmacological activities, thus various hydantoin derivatives with cyclic modification of the parent structure were synthesized as possible anticonvulsant and analgesic activities. These Compounds were prepared by condensation of 3–N-p-substituted phenyl hydantoin with phenyl cyanamide to form 3-N-(p- substituted phenyl) – 1-N-(N-phenyl guanidyl) amidino hydantoin. The purity of the compounds were checked on thin layer chromatography (TLC). The compounds were analyzed for elemental analysis, the structure of compounds were characterized by Infra-red (IR) spectroscopy and nuclear magnetic spectroscopy (NMR). The compounds were screened for anticonvulsant and analgesic activities.

Keywords

hydantoinsynthesisanticonvulsantanalgesicactivity

Citation record

How to cite this article

Roopali Tandon, Ved Prakash Singh, S. C. Mehra (2024). Synthesis of Some New Hydantoin Derivatives with Possible Anticonvulsant and Analgesic Activities. Procedure International Journal of Science and Technology, 1(6), 30–36. https://doi.org/10.62796/pijst.2024v1i605

Roopali Tandon, Ved Prakash Singh, S. C. Mehra. “Synthesis of Some New Hydantoin Derivatives with Possible Anticonvulsant and Analgesic Activities.” Procedure International Journal of Science and Technology, vol. 1, no. 6, 2024, pp. 30–36. https://doi.org/10.62796/pijst.2024v1i605

Roopali Tandon, Ved Prakash Singh, S. C. Mehra. “Synthesis of Some New Hydantoin Derivatives with Possible Anticonvulsant and Analgesic Activities.” Procedure International Journal of Science and Technology 1, no. 6 (2024): 30–36. https://doi.org/10.62796/pijst.2024v1i605

Roopali Tandon, Ved Prakash Singh, S. C. Mehra (2024) ‘Synthesis of Some New Hydantoin Derivatives with Possible Anticonvulsant and Analgesic Activities’, Procedure International Journal of Science and Technology, 1(6), pp. 30–36. Available at: https://doi.org/10.62796/pijst.2024v1i605.

Roopali Tandon, Ved Prakash Singh, S. C. Mehra, “Synthesis of Some New Hydantoin Derivatives with Possible Anticonvulsant and Analgesic Activities,” Procedure International Journal of Science and Technology, vol. 1, no. 6, pp. 30–36, 2024. https://doi.org/10.62796/pijst.2024v1i605.

Roopali Tandon, Ved Prakash Singh, S. C. Mehra. Synthesis of Some New Hydantoin Derivatives with Possible Anticonvulsant and Analgesic Activities. Procedure International Journal of Science and Technology. 2024;1(6):30–36. https://doi.org/10.62796/pijst.2024v1i605.

Roopali Tandon, Ved Prakash Singh, S. C. Mehra. Synthesis of Some New Hydantoin Derivatives with Possible Anticonvulsant and Analgesic Activities. Procedure International Journal of Science and Technology 2024, 1 (6), 30–36. https://doi.org/10.62796/pijst.2024v1i605.

Record provenance

Publication history

Published30 Jun 2024
DOI assigned30 Jun 2024
Record versionVersion of Record

Research integrity

Declarations

Funding

No separate funding declaration was available in the verified source record; the journal policy applies.

Conflict of Interest

No separate conflict-of-interest declaration was available in the verified source record; the journal policy applies.

Ethical Approval

No separate ethical approval statement was available in the verified source record; the article and journal policies apply.

Data Availability

No separate data-availability statement was available in the verified source record; contact the author(s) or editorial office where appropriate.

Author Contributions

No separate author-contribution statement was available in the verified source record; authorship follows the published article record.

AI-use Declaration

No separate AI-use declaration was available in the verified source record; the journal AI-use policy applies.

Editorial record

Publisher's Note

The views, opinions and conclusions expressed in this article are those of the author(s). Publication does not imply endorsement by the journal, editorial board or publisher. Responsibility for accuracy, originality and integrity remains with the author(s). Readers should independently evaluate and verify information before application or citation.

Open-access terms

License & Copyright

Copyright © 2024 Author(s). This work is published by Procedure International Journal of Science and Technology under the Creative Commons Attribution-NonCommercial 4.0 International. Authors retain copyright and grant the journal the right of first publication.

Source record

References

Showing first 3 of 13 references.

  1. Eisman, P.C., Konopka, E. A., and Mayer, R. L. Antituberculous activity of substituted thioureas. III. Activity in guinea pigs. (1954) Am. Rev. Tubere.,70.
  2. Mackenzie, C.G., Maekenzie, J.B., and M.C. Collum, E.V. The prevention by alpha-tocopherol of “cod liver oil muscular dystrophy” in the rabbit. (1941) Science.,94 (518).
  3. Mackenzie, C.G., and Maekenzie, J.B. Effect of sulfonamides and thioureas on the thyroid gland and basal metabolism. (1943) Endocrinology., 32 (185).

Discover more

Related articles