: Identifying promising pharmaceutical compounds is challenging, but computational techniques have revolutionized early drug discovery by enabling efficient screening using criteria like Lipinski’s Rule of Five. This approach saves time and resources in selecting potential drug candidates. A series of novel Schiff base-coumarin derivatives was designed using in silico methods and subsequently synthesized as potential antimicrobial agents. The synthesized compounds were evaluated for their antibacterial and antifungal activities. In silico analysis confirmed that all the compounds comply with Lipinski’s Rule of Five, indicating favorable drug-like properties.
Keywords
Lipinski’s Rule of Fivenovel Schiff base-coumarinsilico methodsantimicrobial agents
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Manisha, Anita Singh, Pravin K. Singh (2025). Synthesis and Characterization of Schiff Base–Coumarin Hybrid. Procedure International Journal of Science and Technology, 2(6), 1–7. https://doi.org/10.62796/pijst.2025v2i6001
Manisha, Anita Singh, Pravin K. Singh. “Synthesis and Characterization of Schiff Base–Coumarin Hybrid.” Procedure International Journal of Science and Technology, vol. 2, no. 6, 2025, pp. 1–7. https://doi.org/10.62796/pijst.2025v2i6001
Manisha, Anita Singh, Pravin K. Singh. “Synthesis and Characterization of Schiff Base–Coumarin Hybrid.” Procedure International Journal of Science and Technology 2, no. 6 (2025): 1–7. https://doi.org/10.62796/pijst.2025v2i6001
Manisha, Anita Singh, Pravin K. Singh (2025) ‘Synthesis and Characterization of Schiff Base–Coumarin Hybrid’, Procedure International Journal of Science and Technology, 2(6), pp. 1–7. Available at: https://doi.org/10.62796/pijst.2025v2i6001.
Manisha, Anita Singh, Pravin K. Singh, “Synthesis and Characterization of Schiff Base–Coumarin Hybrid,” Procedure International Journal of Science and Technology, vol. 2, no. 6, pp. 1–7, 2025. https://doi.org/10.62796/pijst.2025v2i6001.
Manisha, Anita Singh, Pravin K. Singh. Synthesis and Characterization of Schiff Base–Coumarin Hybrid. Procedure International Journal of Science and Technology. 2025;2(6):1–7. https://doi.org/10.62796/pijst.2025v2i6001.
Manisha, Anita Singh, Pravin K. Singh. Synthesis and Characterization of Schiff Base–Coumarin Hybrid. Procedure International Journal of Science and Technology 2025, 2 (6), 1–7. https://doi.org/10.62796/pijst.2025v2i6001.
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